Ph.D, Miami Univ. (OH), Experimental Psychology; Postdoctoral training at Harvard Medical School, Catholic University of America, and National Institute of Mental Health
Dr. Yang Jiang is a tenured Professor and the Head of the Aging, Brain, and Cognition Laboratory in the Department of Behavioral Science, College of Medicine, University of Kentucky. She is also an affiliated faculty investigator at the Alzheimer’s Disease Research Center, Sanders-Brown Center on Aging, and Magnetic Resonance Imaging and Spectroscopy Center, in the College of Medicine, and a joint appointment in the Department of Psychology, College of Arts and Sciences, University of Kentucky, as well as a Research Physiologist at the Lexington Veterans Affairs (VA) Medical Center.
Dr. Jiang has broad training and expertise in behavioral neuroscience (neuroimaging) and experimental psychology (Ph.D. Psychology, Miami University, OH). Her postdoctoral training includes monkey physiology (Neurobiology, Harvard Medical School, Boston, MA), human electrophysiology in cognitive aging (Psychology, The Catholic University of America, DC), and functional magnetic resonance imaging (fMRI) in cognition, National Institute of Mental Health (NIH, Bethesda, MD).
Professor Jiang’s laboratory has been studying sensory perception and cognitive functions in young and older adults and patients with mild cognitive impairments due to dementia, traumatic brain injury, or other mental disorders. Her federal-funded projects include developing neuro-signatures for prediction, prevention, and treatment of cognitive decline. Additionally, her lab has been gauging individual differences in human behavior, brain responses (measured by EEG, MEG, MRI), and genetics associated with cognitive and affective processes.
Dr. Jiang’s research focuses on understanding the neural mechanisms underlying visual perception and cognition in healthy and clinical populations. Her lab is using approaches of psychophysics and cognitive neuroscience, such as functional magnetic resonance imaging (fMRI), and event-related potentials (ERPs). The current projects include developing neurosignatures of memory malfunction and cognitive impairment due to aging or brain damage, and measuring individual differences in behavior, brain responses and genetics associated with cognitive and affective processes.
Principal Investigator, "Predictive neurophysiological biomarkers for risk of Alzheimer’s Disease and Related Dementia induced cognitive impairment in Sino-US Cohorts" (PI Jiang), National Institute of Aging, 2018-2021.
Principal Investigator, Tuning Up Memory-related Brain Potentials using Real-time Neurofeedback in Older Veterans (PI Jiang), Department of Veterans Affairs, 2020-2022.
Co-Investigator, "A Multiscale Multimodal Diffuse Optical Device for Early Detection of Preclinical Alzheimer’s Disease" (PI Yu), National Institute of Health, 2019-2022.
Co-Investigator, "Chemotherapy Induced Cognitive Impairment: Stage 2 study of 'Chemo brain' in Ovarian Cancer Patients" (Miller), Department of Defense, Ovarian Cancer Research Program, Congressionally Directed Medical Research Programs, 2015-2019.
Principal Investigator, "Neuroimaging-Genetic biomarkers to identify risk and treatment efficacy in combat TBI and PTSD" (Jiang), Henry M. Jackson Foundation for the Advancement of Military Medicine, 2015-2019.
Co-Investigator, “Individual Differences in sensation seeking status”, National Institute of Drug Abuse, P50 DA005312 to UK CDART center (PI Bardo), 2008-2019.
Co-Investigator, “Noninvasive optical assessment of cerebrovascular disease in an older population” Sanders-Brown Center on Aging and UK CCTS Pilot Project (Yu), National Institute on Aging, 5P30AG028383-08 (Van Eldik), 2013-2014
Principal Investigator, “Genetic contribution to individual differences in risk-taking behavior”, Center for Drug Abuse Research Translation Pilot Project (PI Jiang), National Institute on Drug Abuse 5P50DA005312-21 (Bardo), 2011-2012.
Co-Investigator, “Individual Differences in reward and inhibition”, National Institute of Drug Abuse, P50 DA005312 (PI Bardo), 2008-2013.
Co-Principal Investigator, “Alzheimer's disease detection via non-linear analysis of EEG”, Department of Energy, DE-AC05-OR22725 to Ork Ridge National Laboratory (dual PIs Jiang & Smith), 6/2005-9/09.
Principal Investigator, "Brain imaging of visual memory for dynamic 3-D objects" Pilot grant (PI Jiang), part of NIH P50 AG05144-21 to Alzheimer Disease Research Center (Markesbery), 5/2004-3/07.
Principal Investigator, "NeuroImaging of complex motion in young and old", National Institute of Aging (NIA), NIH, K01 AG00986 (PI Jiang), 9/2001-8/07.
Jiang, Y, Li, J, Schmitt, F, Jicha, GA, Munro, N, Zhao, X, Smith, C, Kryscio, R, & Abner, E (2021). Memory-related frontal brainwaves predict transition to mild cognitive impairment in cognitively intact older individuals five years before diagnosis, Journal of Alzheimer's Disease, vol. vol. 79, no.2, pp. DOI: 10.3233/JAD-200931. https://content.iospress.com/articles/journal-of-alzheimers-disease/jad200931
Borhani, S, Zhao, X, Kelly, MR, Gottschalk, KE, Yuan, F, Jicha, GA, & Jiang, Y (2021). Gauging working memory capacity from differential resting brain oscillations in older individuals with a wearable device, Frontiers in Aging Neuroscience, 13:625006. doi: 10.3389/fnagi.2021.625006 https://www.frontiersin.org/articles/10.3389/fnagi.2021.625006/full
Babiloni, C, Arakaki, X, Azami, H, … Jiang, Y,…et al. (2021). Measures of resting state EEG rhythms for clinical trials in Alzheimer's disease: Recommendations of an expert panel. Alzheimer's Dement.; 1- 26. https://doi.org/10.1002/alz.12311
Yan, S, Xu, R, Stratton, TD, Kavcic, V, Luo, D, Hou, F, Bi, F, Jiao, R, Song, K, & Jiang, Y (2020). Sex differences and psychological stress: responses to the COVID-19 pandemic in China, BMC Public Health, 21:79. https://rdcu.be/ceEHx
Neal, J, Strothkamp, S, Bedingar, E, Cordero, P, Wagner, B, Vagnini, V, & Jiang, Y (2019). Discriminating fake from true brain injury using latency of left frontal neural responses during Old/New memory recognition, Frontiers in Neuroscience, Decision Neuroscience, doi.org/10.3389/fnins.2019.00988
Broster, SL, Li, J, Smith, C, Jicha, G, Schmitt, F, Munro, N, Haney, R, & Jiang, Y (2018). Spared behavioral repetition effects in Alzheimer’s disease linked to an altered neural mechanism at posterior cortex, Journal of Clinical and Experimental Neuropsychology, DOI:10.1080/13803395.2018.1430230
Jiang, Y, Zhao, X, Abiri, R (2017). Tuning up the old brain with new tricks: Attentional training via neurofeedback, Front. Aging Neurosci. 9:52. doi: 10.3389/fnagi.2017.00052. | https://doi.org/10.3389/fnagi.2017.00052
Li, J, Broster, L, Jicha, G, Munro, N, Schmitt, F, Abner, E, Kryscio, R, Smith, C, & Jiang, Y (2017). A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging, Alzheimer's Research & Therapy, 9:3. DOI: 10.1186/s13195-016-0229-3 [PubMed]
Jiang, Y, Lin MK, Jicha GA, Ding X, McIlwrath SL, Fardo DW, Broster LS, Schmitt FA, Kryscio R, Lipsky RH (2017). Functional human GRIN2B promoter polymorphism and variation of mental processing speed in older adults. Aging (Albany NY). 2017; 9:1293-1306. doi: 10.18632/aging.101228
Broster, LS, Jenkins, SL, Tarrant, SD, Jicha, GA, Jiang, Y (2017). Low arousal positive emotional stimuli attenuate aberrant working memory processing in persons with mild cognitive impairment, Journal of Alzheimer's Disease, 60 (4), 1333-1349, DOI 10.3233/JAD-170233.
Jiang, Y, Huang, H, Abner, E, Broster, LS, Jicha, G, Schmitt, F, Kryscio, R, Andersen, A, Powell, D, van Eldik, L, Gold, B, Nelson, P, Smith, C, & Ding, M (2016). Alzheimer’s biomarkers are correlated with brain connectivity in older adults differentially during resting and task states, Frontiers in Aging Neuroscience, 8: 15. doi: 10.3389/fnagi.2016.00015
Chester, D, DeWall, CN, Derefinko, K, Estus, S, Lynam, DR, Jiang, Y (2016). Looking for reward in all the wrong places: Dopamine receptor gene polymorphisms correlate with aggression through greater sensation-seeking, Social Neuroscience, 11, 487-494.
McBride, J, Zhao, X, Munro, N, Jicha, G, Schmitt, FA, Kryscio, RJ, Smith, C, & Jiang, Y (2015), Sugihara causality analysis of scalp EEG for detection of early Alzheimer's Disease, NeuroImage: Clinical, 7: 258–265. [PubMed]
Downer, B, Jiang, Y, Zanjani, F, & Fardo, D (2014). Effects of alcohol consumption on cognition and regional brain volumes among older adults, American Journal of Alzheimer's Disease and Other Dementias, E-Pub September 7, 2014, doi: 10.1177/1533317514549411.
Broster, LS, Li, J, Smith, C, Jicha, G, Schimitt, F, & Jiang, Y (2013). Repeated retrieval during working memory is sensitive to amnestic mild cognitive impairment, Journal of Clinical and Experimental Neuropsychology, 35 (9): 946-59.
Xu, P, Gu, R, Broster, L, Wu, R, Van Dam, N, Jiang, Y, Fan, J, & Luo, Y (2013). Neural basis of emotional decision making in trait anxiety, Journal of Neuroscience, 33 (47): 18641-18653.
McBride, J, Zhao, X, Munro, N, Smith, C, Jicha, J, & Jiang, Y (2013). Resting EEG discrimination of early Alzheimer’s disease from normal aging using inter-channel coherence network graphs. Annals of Biomedical Engineering, 41 (6), 1233-1242.
Parasuraman, R & Jiang, Y (2012). Individual differences in cognition, affect, and performance: Behavioral, neuroimaging, and molecular genetic approaches, NeuroImage, 59 (1), p70-82.
Broster, LS, Blonder, L, & Jiang, Y (2012). Does emotional memory enhancement assist the memory-impaired? A mini-review, Frontiers in Aging Neuroscience, 4:2. doi: 10.3389/fnagi.2012.00002.
Lawson, A, Liu, X, Joseph, J, Vagnini, V, Thomas, KH, Jiang, Y (2012). Sensation seeking predicts brain responses in the old-new task: converging multimodal neuroimaging evidence, International Journal of Psychophysiology, 84(3): 260-9; doi: 10.1016/j.ijpsycho.2012.03.003.
Jiang, Y, Lianekhammy, J, Lawson, A, Guo, C, Lynam, D, Joseph, J, Gold, BT, & Kelly, TH. (2009). Brain responses to repeated visual experience among low and high sensation seekers: role of boredom susceptibility, Psychiatry Research: NeuroImaging, 173, 100-106.
Jones, WJ, Childers, TL, & Jiang, Y (2012). The shopping brain: mathematical anxiety modulates brain responses to buying decisions, Biological Psychology, 89, 201-213. doi:10.1016/j.biopsycho.2011.10.011.
Jiang, Y, Luo, YJ, & Parasuraman, R. (2009). Neural mechanisms underlying age-related reduction in visual motion priming, Aging, Neuropsychology, and Cognition, 16(2): 164-82.
Ding, JH, Powell, D, & Jiang, Y (2009). Dissociable frontal controls during visible and memory-guided eye-tracking of moving targets, Human Brain Mapping, 30:3541-3552.
Jiang, Y, Boehler, CN, Nönnig, N, Düzel, E, Hopf, JM, Heinze, HJ, & Schoenfeld, MA (2008). Spatial-temporal analysis of binding 3D shape perception, Journal of Cognitive Neuroscience, 20, (4), 553-562.
Guo, CY, Lawson, A, Zhang, Q, & Jiang, Y (2008). Brain potentials of new and studied objects during working memory, Human Brain Mapping, 29, (4), 441-452 (Cover Illustration).
Jiang, Y, Ding, JH, Gold, BT, & Powell, D (2008). The hemispheric asymmetries in tracking occluded moving targets with the mind’s eye: Simultaneous event-related fMRI and eye-movement recording, Brain Imaging and Behavior, 2: (4), 300-308.
Lawson, AL,Guo, C, & Jiang, Y (2007). Age effects on brain activity during repetition priming of targets and distracters, Neuropsychologia, 45, 1223-1231.
Guo, CY, Lawson, A, & Jiang, Y (2007). Two distinct neural mechanisms of repetition priming, Neuroscience, 149, 747-759.
Zhang, Q, Guo, C, Lawson, A, & Jiang, Y (2006). Electrophysiological correlates of visual affective priming, Brain Research Bulletin, 71, 316-323.
Jiang, Y, Luo, YJ, & Parasuraman, R (2002). Neural correlates for perceptual priming of visual motion. Brain Research Bulletin, 57 (2), 211-219.
Jiang, Y, Haxby, JV, Martin, A, Ungerleider, LG, & Parasuraman, R (2000). Complementary neural mechanisms for tracking familiar items in human working memory. Science, 287, 643-646.