Craig R. Rush, Ph.D. - Principal Investigator
William W. Stoops, Ph.D. - Principal Investigators
465 East High Street, Suite 204B
Lexington, KY 40507
Fax: (859) 257-7684
The Laboratory of Human Behavioral Pharmacology (LHBP), a research unit in the Department of Behavioral Science at the University of Kentucky Chandler Medical Center, was established in 1999 and is currently directed by Dr. Craig R. Rush. The mission of the LHBP is two-fold. First, through its research, the LHBP aims to elucidate the biological, pharmacological and environmental factors that contribute to substance abuse. Current research activities in the Laboratory of Human Behavioral Pharmacology (LHBP) are also focused on identifying putative pharmacotherapies for the management of stimulant dependence.
Compounds from diverse pharmacological classes are being studied including monoamine reuptake inhibitors, anxiolytics and opioid antagonists. Research in the LHBP uses principles of pharmacology and behavioral analysis to determine the behavioral and neuropharmacological underpinnings of drug abuse and dependence. Facilities are available for the conduct of outpatient and inpatient studies. Drug effects are assessed using a variety of behavioral, cognitive, cardiovascular and physiological assays. A computerized data-collection system custom designed for the conduct of human behavioral pharmacology studies is used, which completely automates the collection of relevant behavioral and physiological data. Because the behavioral and neuropharmacological effects of drugs contribute to their abuse, the research activities conducted at LHBP provide basic information that is necessary for the development of improved behavioral treatments as well as for the development of medications to treat alcohol and drug abuse. These research activities are primarily funded by the National Institute on Drug Abuse (NIDA). Second, the LHBP has as its mission to train pre-doctoral and post-doctoral fellows, medical students and psychiatry residents in substance-abuse research.